Ace the SkillsUSA Medical Terminology Challenge 2026 – Decode, Define, and Dominate!

Enlargement is indicated by the suffix -megaly, which means an enlarged organ or body part. It attaches to the name of the organ to describe its increased size—examples include hepatomegaly (enlarged liver), cardiomegaly (enlarged heart), and acromegaly (enlargement of the extremities). The other suffixes have different meanings: -emia refers to a blood condition, -itis denotes inflammation, and -plasia means development or formation of tissue, not specifically enlargement.